Until beginning of the 1990s, the centre of Amsterdam was regarded as the obvious nucleus of urban and regional economic activity. But since then, issue of accessibility and scale have prompted the development of multi-nodal spatial networks on a regional scale. In ten years’ time the spatial and economic configuration of the region has changed dramatically. The development of the Zuidas or ‘southern axis’ district in the coming thiry years offers a strategic opportunity to furnish this regionalization of urbanity with a new, more appealing structure. After all, the Zuidas is not only emerging as a business centre of international significance, its favourable position in the traffic and transport system provides it with optimum conditions for evolution into a varied urban-centre environment.